pmol to mg Converter
To convert pmol to mg, multiply the value in picomoles by the molecular weight (g/mol), then divide by 1,000,000,000.
How to Convert pmol to mg
Use this pmol to mg converter to change picomoles into milligrams. Enter pmol and the molecular weight.
pmol × MW gives picograms. One milligram is 109 picograms, so mg = pmol × MW ÷ 109.
For example, 1,000,000 pmol (1 µmol) of ATP (free acid, MW 507.182 g/mol) is 0.507182 mg.
mg = pmol × MW ÷ 1,000,000,000Multiply the picomoles by the molecular weight (g/mol), then divide by 1,000,000,000 (10⁹) to get milligrams.Conversion Formula
The formula to convert pmol to mg is:
Where:
- pmol = amount in picomoles (10⁻¹² mol)
- mg = mass in milligrams (10⁻³ g)
- MW = molecular weight (molar mass) in g/mol
Conversion Table
Common pmol to mg conversions are shown below. The last column uses ATP (MW 507.182 g/mol) as an example.
| pmol | mg (formula) | mg for ATP |
|---|---|---|
| 0.01 | 1 × 10⁻¹¹ × MW | 5.07182 × 10⁻⁹ |
| 0.1 | 1 × 10⁻¹⁰ × MW | 5.07182 × 10⁻⁸ |
| 0.33 | 3.3 × 10⁻¹⁰ × MW | 1.6737006 × 10⁻⁷ |
| 0.5 | 5 × 10⁻¹⁰ × MW | 2.53591 × 10⁻⁷ |
| 1 | 1 × 10⁻⁹ × MW | 5.07182 × 10⁻⁷ |
| 2.5 | 2.5 × 10⁻⁹ × MW | 0.000001267955 |
| 5 | 5 × 10⁻⁹ × MW | 0.00000253591 |
| 10 | 1 × 10⁻⁸ × MW | 0.00000507182 |
| 33 | 3.3 × 10⁻⁸ × MW | 0.000016737006 |
| 50 | 5 × 10⁻⁸ × MW | 0.0000253591 |
| 100 | 1 × 10⁻⁷ × MW | 0.0000507182 |
| 250 | 2.5 × 10⁻⁷ × MW | 0.0001267955 |
| 500 | 5 × 10⁻⁷ × MW | 0.000253591 |
| 1,000 | 0.000001 × MW | 0.000507182 |
Worked Examples
Here are some common examples of pmol to mg conversion, using ATP (MW 507.182 g/mol):
- 5.07182 × 10⁻⁷ mg = 1 pmol
- 0.00000253591 mg = 5 pmol
- 0.000016737006 mg = 33 pmol
- 0.0000507182 mg = 100 pmol
Unit Definitions
What is a picomole (pmol)?
A picomole (pmol) is a unit of amount of substance equal to 10⁻¹² mole.
The prefix pico- (p) means 10⁻¹², or one trillionth. So 1 pmol = 0.000000000001 mol.
What is a milligram (mg)?
A milligram (mg) is a unit of mass equal to 10⁻³ gram.
The prefix milli- (m) means 10⁻³, or one thousandth. So 1 mg = 0.001 g.
Why Is Molecular Weight Needed?
Moles count particles. Grams measure mass. One particle of each substance has its own mass, so the link between them is the molecular weight (MW), also called molar mass.
MW tells you how many grams one mole of a substance weighs. For example, one mole of water weighs about 18.015 g, while one mole of glucose weighs about 180.16 g.
Therefore, to convert pmol to mg, you multiply by MW, then divide by 1,000,000,000. The extra step (÷ 1,000,000,000) only adjusts for the different sizes of the two units.
Uses and Importance of pmol and mg
Picomoles are tiny, so the answer in mg is usually a very small decimal. This conversion is mainly used to check how much bulk material a pmol-scale experiment really uses.
Material budgeting
Even thousands of reactions at a few pmol each use only a small fraction of a milligram.
Bioluminescence assays
ATP assays detect very small amounts. Converting pmol to mg shows how little ATP is involved.
Supplier comparisons
Products sold in mg can be compared with experimental needs in pmol.
Frequently Asked Questions (FAQ)
How many mg is 1 pmol of ATP?
1 × 507.182 ÷ 109 ≈ 5.072 × 10−7 mg.
Why divide by a billion?
pmol × MW gives pg, and 1 mg = 109 pg.
How many pmol of ATP are in 1 mg?
1 mg ÷ 507.182 × 109 ≈ 1,972,000 pmol, which is about 2 million pmol.
Which form of ATP does the example use?
The free acid (C₁₀H₁₆N₅O₁₃P₃). Salt forms such as disodium ATP are heavier.
Can I weigh 1 pmol of anything?
No. It is far below what a balance can measure. Use a stock solution and dilute it.
Other Related Tools
Accuracy and Scope
The example uses the free acid form of ATP; use the molecular weight on your product label.
The result depends on the molecular weight you enter.
Sources